
Sarecycline free base
CAS No. 1035654-66-0
Sarecycline free base( —— )
Catalog No. M23244 CAS No. 1035654-66-0
Sarecycline free base is a tetracycline-derived, narrow-spectrum antibiotic.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
1G | 4928 | In Stock |
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Biological Information
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Product NameSarecycline free base
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NoteResearch use only, not for human use.
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Brief DescriptionSarecycline free base is a tetracycline-derived, narrow-spectrum antibiotic.
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DescriptionSarecycline free base is a tetracycline-derived, narrow-spectrum antibiotic.
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In Vitro——
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In VivoAnimal Model:Carrageenan-induced footpad edema male Sprague Dawley rats modelDosage:1 mg/kg, 5 mg/kg ,10 mg/kg, 25 mg/kg, 50 mg/kg, 75 mg/kg,100 mg/kg, 150 mg/kg Administration:Intraperitoneal injection (i.p.); Single dose. Before a subplantar injection of sterile 1 mg/0.1 mL carrageenan solution in the right hind paw.Result:Reduced inflammation to 55.7% and 53.1%, respectively, at doses of 75 mg/kg and 100 mg/kg compared to baseline.Animal Model:Carrageenan-induced footpad edema male Sprague Dawley rats model Dosage:0.33, 1, 3, or 9?mg/kg Administration:Intravenously Result:Achieved a 2-log10 reduction in the bacterial burden in the thigh at a dose comparable to that of doxycycline, with ED50s of 8.23 and 8.32?mg/kg, respectively.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1035654-66-0
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Formula Weight487.5
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Molecular FormulaC24H29N3O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (205.13 mM)
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SMILESCN(C)[C@@H]([C@H](C[C@H](Cc1c(CNCOC)ccc(O)c1C1=O)C1=C1O)[C@]11O)C(O)=C(C(N)=O)C1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Pinazo A , Manresa M A , Marques A M , et al. Amino acid–based surfactants: New antimicrobial agents[J]. Advances in Colloid and Interface Science, 2016, 228:17-39.
molnova catalog



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